University of Ghana Stadium (Friday)
- Eleven Wonders 0–2 Swedru All Blacks
Kwame Kyei Sports Complex (Saturday)
- Nations FC 2–1 Heart of Lions
Nii Adjei Kraku II Sports Complex
- Vision FC 0–0 Young Apostles
Tuba Astro Turf
- Dreams FC 2–1 Bechem United
TNA Stadium
- Medeama SC 2–1 Berekum Chelsea
Nsenkyire Sports Arena
- FC Samartex 2–0 Gold Stars SC
Nana Agyemang Badu I Park
- Aduana FC 0–0 Basake Holy Stars
Hohoe Sports Stadium
- Hohoe United 1–0 Asante Kotoko
Aliu Mahama Stadium
- Karela United 2–0 Hearts of Oak
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